Myxofibrosarcoma in Varicose Vein: A Cases Report

靜脈曲張中的黏液纖維肉瘤：病例報告

葉彥良(Yen-Liang Yeh) ； 趙家聲(Chia-Sheng Chao) ； 陳仁智(Ren-Zhi Chen)

《南臺灣醫學雜誌》 14卷1期 (2018/06) Pp. 56-59

https://doi.org/10.6726/MJST.201806_14(1).0008

摘要

Myxofibrosarcoma (MFS) is a rare soft tissue neoplasmscharacterized by a high frequency of local recurrence due to an infiltrative growth property. Most common presents in the extremities of elderly people. The clinical presentation is not pathognomonic and the histological aspects are highly heterogenous, frequently delaying the diagnosis or leading to misdiagnosis. Complementary histochemical and immune-histochemical staining are mandatory to achieve the diagnosis of MFS. A 54-year-old female patient is presented with myxofibrosarcomain varicose vein on right calf. Local recurrent mass lesion was found three months later after excision of thrombosis varicose veins. Wide excision of right calf mass lesion was done and pathology showed myxofibrosarcoma. Wide excision with adequate safe margin should be recommended to prevent a local recurrence. The overall risk of distant metastases is significant which makes worse prognosis.

關鍵字

myxofibrosarcoma ； varicose vein ； wide excision ； local recurrence ； distal metastasis

並列摘要

黏液纖維肉瘤是一種罕見極度侵犯性的軟組織惡性腫瘤。最常以容易局部復發的四肢腫塊來表現，好發於年長者。臨床表現有高度的變異性因此常造成延遲診斷或誤診的情況。病理診斷需藉由免疫及組織化學染色來達成。這篇文章提出一個54歲女性接受右小腿靜脈曲張切除手術後三個月，傷口處又長出新的腫塊，第二次手術廣泛切除病灶後，病理證實是黏液纖維肉瘤。病灶廣泛切除合併適當的手術安全邊界以降低局部復發的機率。若合併有遠端轉移則有較差的預後。

並列關鍵字

黏液些纖維肉瘤 ； 靜脈曲張 ； 廣泛切除 ； 局部復發 ； 遠端轉移