The main purpose of this research is to examine the arbitrage opportunity and profit of the Mini-TAIEX Futures (MTX) and Taiwan Stock Index Options (TXO) for the period January 1, 2009 to December 12, 2012. First, the results show that whether taking into account transaction costs or not, investors could execute arbitrage trading between MTX and TXO to earn significant ex-post arbitrage profits. Second, the positive basis group has higher arbitrage opportunities than negative basis group. However, the negative basis group has higher arbitrage profit than positive basis group. Finally, we demonstrate the issue by regression analysis. The results indicate that the total spread cost, volatility, call option price level inside and outside and arbitrage strategy are negatively related to arbitrage profit. Number of days to maturity and degree of outside contract price are positively related to arbitrage profit.