- 期刊
Searching the Regulatory Protein Binding Site by Steepest Ascent Algorithm
並列摘要
Gene transcription regulation impacts the final expression of gene. Generally gene expression is regulated via an interaction between regulatory proteins and specific DNA elements. If we find out the binding sites of regulatory factors, we could understand more of the control mechanism of gene transcription. For this reason, it is a very important issue to find out the regulatory factors of gene transcription. We propose a method to find out the regulatory protein binding sites from the comparisons of DNA sequences and scoring matrices. The steepest ascent algorithm is adopted to search the possible locations of binding sites. The predicted results of regulatory protein binding sites are shown with tables and charts. The proposed system in this paper will help biologists to analyze the regulatory protein binding sites more efficiently.
被引用紀錄
延伸閱讀
- 劉建德（2008）。Prediction of DNA-binding sites in protein sequences〔碩士論文，元智大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0009-0307200820281100
- Chiu, C. C. (2007). Prediction and Pattern Analysis of Protein secondary structure [master's thesis, National Tsing Hua University]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0016-1411200715151226
- Kuo, Y. C. (2009). Identification and Search of Protein Structural Motif [master's thesis, National Chiao Tung University]. Airiti Library. https://doi.org/10.6842/NCTU.2009.00734
- Huang, Y. F. (2010). A Study of Prediction of Protein Binding Residues [doctoral dissertation, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2010.10695
- 蕭國慶（2005）。Analysis of protein secondary structures and residues environment〔碩士論文，亞洲大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0118-0807200916271782