Tire/pavement interaction has been an important research topic in pavement engineering for many years. Rutting and fatigue cracking are two import ant concerns that govern the pavement structure design. The allowable number of load repetitions to limit rutting and fatigue cracking are predicted based on the tensile stress or strain at the bottom of asphalt concrete layer and compressive strain at the top of subgrade. Traditionally, strains are calculated using multilayer elastic formulation based on the predefined contact area either circular or rectangular, which are not very accurate. A fully dynamic tire/pavement interaction satisfying impenetrability and traction conditions cannot be achieved with empirical approaches. Therefore solutions of stresses and strains at concerned place s of pavement structure are not reliable. This paper presents a fully tire/pavement interaction finite element model that can effectively include the dynamic effect of tire rolling to the calculation of pavement response. The tire is modeled as a finite strain hyperelastic material, and the pavement structure is modeled as elastic materials. A finite strain hyperelasticity is introduced for modeling of rubber tire, which was implemented as a user subroutine in ABAQUS. Representative simulations are provided to demonstrate how the tire/pavement interaction model can be used to predict pavement response and pavement damage due to fatigue cracking and rutting in the field of pavement engineering.