Asphalt mixture with Mafilon (abbreviated as MFL) is an automatic long-term snowmelt asphalt mixture, which replaces fine minerals and helps in the deicing process. To validate the performance of asphalt mixture with MFL content, some indoor tests were conducted. We investigated the field deicing capacity of the asphalt mixture, and compared the performance of several asphalt mixtures with different MFL contents. The results showed the following: (1) under the same gradation, the automatic long-term snowmelt asphalt mixtures displayed better anti-rutting performance, and the MFL content only slightly affected the low-temperature performance of the asphalt mixture; and (2) the moisture stability of three kinds of asphalt mixture met the specification requirement, although it decreased with the increase in MFL content. Based on the indoor and outdoor deicing effects of the asphalt mixture, more MFL contents in the asphalt mixture could result in better pavement deicing.