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Nutritional and Hematological Recovery of Severely Malnourished Children with New Flour Formulas Developed at Ouagadougou (Burkina Faso)

並列摘要


A longitudinal study was carried out, which tested the efficacy of severe malnutrition recovery with Misola and two experimental flours produced with local products (seeds of Moringa oleifera and Cucurbita maxima, pulps of Adansonia digitata and Parkia biglobosa), supplemented with Zea mays (F1) or Pennisetum glaucum (F2). A total of 187 severely malnourished children aged 6 to 36 months were enrolled in the study and randomly assigned to one of three treatment groups, in order to compare the effects of the experimental flours with those from Misola (F3), the existing complementary flour used frequently for children recovery. The groups were comparable by nutritional and socioeconomic parameters. Anthropometric and hematological measurements were taken between inclusion and recovery. At recovery, the weight for height (WHZ) increased to 2 and 1 SD, respectively in the three groups. The average weight gain was 6 g/kg/day in the F2 group, compared to 4.5 g/kg/day for the F1 and Misola group. The paired t-test of Midupper Arm Circumference (MUAC) indicated a significant change for each group (p<0.05). Between inclusion and recovery, hemoglobin rate within each group was 8±1 vs 8±1; 9±1 vs 9.5±1 and 10±1 vs 11±1 g/dL, respectively for group F1, F2 and F3. The PPZ was 7.2±6.1 vs 6.2±3.7 μg/g Hb for F1 group, while for group F2 PPZ it was 7.7±4.7 vs 9.2±6.7 μg/g Hb. Lastly, F3 group indicated a PPZ value of 7.5±4.3 vs 8.9±5.7 μg/g Hb. The formulated flours appear to be efficacious in improving nutritional and hematological recovery of severely malnourished children and F2 performed best.

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