新生兒尿液中高尿酸合併血尿一病例報告

Hyperuricosuria with Hematuria in Newborn-Report of One Case

王瑩(Ying Wang) ； 王凱立(Kai-Li Wang) ； 陳遠浩(Yuan-Hao Chen)

《童綜合醫學雜誌》 1卷1期 (2007/12) Pp. 58-61

https://doi.org/10.29838/TMJ.200712.0009

摘要

新生兒血尿之原因不少，但高尿酸之排泄所導致的新生兒血尿並不多見。本病例雖以紅色之尿布呈現，但在相關之檢測中，不僅有血尿之存在，且其尿液中尿酸排泄百分率（FEUA）可高達38%，約為成人（10%）之3～4倍之多，而證實為一高尿酸排泄合併血尿之新生兒病例。這種結果乃因於新生兒之腎小管功能之不足所導致。不過，這種新生兒高尿酸排泄情況只是短暫性的。隨著新生兒腎小管之不斷成熟發育，及其身體中細胞內、外液量之改變，其尿酸之排泄量也就隨之而減少了。

關鍵字

新生兒 ； 高尿液中尿酸 ； 血尿 ； 尿酸排泄率

並列摘要

There were many causes of hematuria in newborn, but it was rarely induced by hyperexcretion of uric acid. Although red diaper was apparent in this case, hematuria was detedted in the correlated tests. Moreover, the value of the fractional excretion of uric acid (FEUA) was up to 38%, as much as 3 to 4 folds in adults (10%). Therefore, hyperuricosuria with hematuria was proved in this case. It may be caused by the impaired function of renal tubules in newborn. However, the hyperexcretion of uric acid in newborn was transient. As the newborn grew-up, the renal tubules matured, and the intracellular and extracellular fluids changed in proportion, the excretion of uric acid was diminished consequently.

並列關鍵字

newborn ； hyperuricosuria ； hematuria ； fractional excretion of uric acid (FEUA)