The skeleton is the second most common site of distant metastasis from renal cell carcinoma. Although radiotherapy and chemotherapy are ineffective in most patients with RCC, surgery is a safe and reliable modality to achieve local tumor control, restore mechanical bone stability, relieve pain, and increase survival. A longer interval between diagnosis of renal cancer and that of osseous metastasis and the absence of extraosseous metastases are predictive of higher survival. Here, we report a case of a 77-year-old male who suffered from a right humeral pathologic fracture caused by metastatic renal cell carcinoma at 12 years post right nephrectomy. He underwent wide excision for the right humeral tumor and had an uneventful 6-month follow-up period.