Transient Splenial Lesions in Children with Influenza-associated Encephalitis/Encephalopathy: A Case Report and Literature Review

兒童之流行性感冒病毒所致腦炎之暫時性胼胝體壓部病兆：病歷報告及文獻綜述

陳柏豪(Bo-Hau Chen) ； 王安慶(Ann-Ching Wang) ； 黃旭瑩(Shi-Ying Huang) ； 陳錫洲(Shyi-Jou Chen)

《童綜合醫學雜誌》 9卷1期 (2015/06) Pp. 30-34

摘要

流行性感冒病毒所造成之腦炎或腦病變，在兒童常造成嚴重的傷害。此篇文章報告一位罹患流行性感冒病毒所造成之腦炎的2歲男童，其腦部核磁共振在擴散權重影像顯示暫時性胼胝體壓部病兆。病童於神經學上的病徵表現快速地改善，並在後續追蹤之腦部核磁共振顯示胼胝體壓部病兆消除。兒童胼胝體壓部病兆案例報導甚少，且尤其是年齡低於五歲之案例。此篇文章報告最年輕之案例，且對此型腦病變其臨床上特殊表現作總結性回顧分析。於本文結論，我們建議當臨床上已診斷流行性感冒病毒相關腦炎，且腦部核磁共振同時只顯示胼胝體壓部之病兆，其臨床上會呈現較佳之病程及好的預後，其進一步侵犯性的檢查可能是不需要的。

關鍵字

流行性感冒 ； 腦炎 ； 胼胝體壓部

並列摘要

Influenza-associated encephalitis/encephalopathy (IAEE) in children often has a grave prognosis. We report a 2-year-old boy with IAEE whose magnetic resonance imaging (MRI) showed a transient splenial lesion on diffusionweighted images. His neurological manifestations quickly improved and were consistent with the resolution of the splenial abnormality on follow-up MRI. Transient splenial lesions in children with IAEE are rarely reported, particularly in children under the age of 5 years. Here, we report the youngest case and review the clinical features of this novel type of encephalopathy. In conclusion, we suggest that when a clinical diagnosis of IAEE is made, and simultaneously, a transient focal lesion in splenium is found on MRI, further investigation is unwarranted if the clinic course and outcome are favorable.

並列關鍵字

Influenza ； encephalitis ； splenium