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Malignant Peritoneal Mesothelioma

腹膜惡性間皮瘤:病例病理報告

摘要


A 78-year-old woman presented with a 2-month history of abdominal pain, fever, nausea, and vomiting. After admission, abdominal computed tomography showed multiple tumors in the abdominal cavity in close contact with the small bowel loops. She underwent exploratory laparotomy, with intraoperative findings of multiple tumors measuring up to 12 cm over the abdominal and pelvic cavities and tumor adhesion to the small intestine, colon, and omentum. Due to the difficulties associated with debulking surgery, two tumor nodules were removed from the omentum for pathologic examination, including immunohistochemistry, which led to the diagnosis of pathological stage III primary peritoneal mesothelioma (MPM). The patient died 1 month after surgery due to aspiration pneumonia with respiratory failure. MPM has a poor prognosis; it is treated with a combination of systemic chemotherapy, intraperitoneal chemotherapy, cytoreductive surgery, and whole-abdominal irradiation. The median survival time for this type of tumor is consistently less than 1 year.

並列摘要


一位76歲女性因腹痛、發燒、噁心及嘔吐二個月求診,入院腹部電腦斷層檢查顯示腹腔內多顆腫瘤和小腸連接。腹腔探查顯示腹腔及骨盆腔內多顆腫瘤和小腸、大腸、腹膜相連接,最大的直徑有12公分。因手術無法完全去除腫瘤,僅取二顆腫瘤以做病理診斷。病理免疫染色後診斷為腹膜惡性間皮瘤,病理分期為第三期。病患於術後一個月因吸入性肺炎及呼吸衰竭而過世。腹膜惡性間皮瘤的預後極差,一般多以化療、手術切除腫瘤及腹部放射線治療為主,平均存活時間少於一年。

並列關鍵字

腹膜腫瘤 間皮瘤 減積手術

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