Tenosynovial Giant Cell Tumor of the Thigh: Pathological and Positron Emission Tomography Findings

肌腱滑液膜巨細胞瘤：病理及正子掃描特徵

曹唐義(Tang-Yi Tsao) ； 李政軍(Zheng-Jun Li) ； 郭璽忠(Xi-Zhong Guo)

《童綜合醫學雜誌》 11卷1期 (2017/06) Pp. 65-68

摘要

Here we present an unusual case of a localized-type tenosynovial giant cell tumor (TGCT) in the left thigh of a 31-year-old woman with a history of colon adenocarcinoma. A restaging whole-body FDG PET/CT revealed a new, intensely FDG-avid soft-tissue mass in the left thigh (SUV = 11.4). Subsequently, magnetic resonance imaging (MRI) also revealed a well-circumscribed soft-tissue tumor (2.1 × 1.8 cm) in the left thigh. Clinically, a metastatic adenocarcinoma was considered. The final pathological diagnosis was a localized-type TGCT, which was confirmed by CT-guided biopsy. Increased FDG uptake in TGCTs can be explained by their high monocyte/macrophage content. In this case, to avoid a false-positive interpretation, radiologists and nuclear medicine physicians must be aware that both metastatic carcinoma and TGCTs can be intensely FDG avid.

關鍵字

tenosynovial giant cell tumor

並列摘要

我們報告一位31 歲女性有大腸癌病史。在PET 分期檢查時發現在左大腿髖部旁有一SUV=11.4 的腫塊，核磁共振檢查也發現在左大腿髖部旁有一2.1 x 1.8 cm 的腫塊，臨床診斷為轉移性病灶，最後病理切片診斷為局部性肌腱滑液膜巨細胞瘤。肌腱滑液膜巨細胞瘤在氟-18- 去氧葡萄糖正子攝影有高吸收值，是因為腫瘤內含有大量單核球及巨噬細胞。針對此病例，轉移癌及肌腱滑液膜巨細胞瘤對氟-18- 去氧葡萄糖正子攝影都有高吸收值，因此放射科及核醫科師要小心不要做出假陽性的誤診。

並列關鍵字

肌腱滑液膜巨細胞瘤