We report a case of a patient with spinal epidural abscess (SEA) after an epidural catheter placement for analgesia during a cesarean section. The parturient was healthy and did not present any risk factors for SEA. Four days postoperatively, worsened back pain and erythema with pus discharge over the epidural insertion site accompanied by sensory deficits in the lower extremities were noted. Magnetic resonance imaging revealed SEA with adjacent inflammation of the paravertebral soft tissue. Emergency laminectomy and SEA removal were performed, followed by a 6-week antibiotic therapy course with vancomycin. The parturient completely recovered from her neurologic deficiencies. In addition, several research articles on SEA were reviewed and discussed in this study.