Recurrent hypoglycemia is not uncommon in patients taking sulfonylurea, especially elder patients with poor renal function. Hypoglycemic hemiparesis is rare and can be misdiagnosed as cerebral infarction. We herein present a case of transient hypoglycemic hemiparesis which developed as recurrent hypoglycemia in an 80-year-old diabetic uremic female. She was sent to the emergency room due to the loss of consciousness. A prompt dextrose supply corrected the situation, but recurrent hypoglycemia and transient hemiparesis developed the next morning. The plasma glucose level was 31 mg/dl and 41 mg/dl, respectively. Early diagnosis of transient hemiparesis and optimal glycemic control is critical in elderly patients, because hypoglycemia may lead to a fatal clinical course if not treated promptly.