Abdominal Obesity and Low Skeletal Muscle Mass Jointly Predicted Total Mortality and Cardiovascular Mortality in Elderly Population

Shao-Yuan Chuang ； Rosalind Chia-Yu Chen ； Wen-Ling Liu ； Yueh-Ying Hsu ； Wen-Harn Pan

《台灣老年醫學暨老年學雜誌》 9卷2期 (2014/05) Pp. 48-48

https://doi.org/10.29461/TGG.201405_9(2).0083

並列摘要

Background: We aimed to investigate the jointed impacts of abdominal obesity and low skeletal muscle mass for cardiovascular and total mortality in elderly population. Materials and methods: A total of 1485 elderly from the National and Health Survey in Taiwanese Elderly (1999-2000) was enrolled, and the survival status was followed using the data from the National Death Registry. The skeletal muscle mass index (SMMI) was calculated by dividing skeletal muscle mass by high in meters squared. The first quartile of SMMI was defined low skeletal muscle mass. Abdominal obesity was defined by simultaneous with high triglycerides (TG) (≥ 150 mg/ dL) and high waist circumference (WC) (≥ 90 cm for men and ≥ 80 cm for women). The Cox proportional hazard model was used to evaluate the jointed impacts of abdominal obesity and low skeletal muscle mass index for cardiovascular disease and total mortality. Results: During the follow-up (median time: 9.2 years), onethird elderly died (n=493) by any cause and 34% of them was cardiovascular mortality (including diabetes; ICD-9-CM: between 390 and 459 for CVD; 250 for diabetes). The total mortality and cardiovascular mortality was 4.2 and 1.4 per 100 person-years. Total mortality in men and women were 4.01 and 2.72, respectively, for normal-TGWC and normal SMMI, 5.73 and 2.82, respectively, for high-TGWC and normal SMMI, 7.07 and 5.91, respectively, for normal TGWC and low SMMI, and 13.92 and 5.77, respectively for high-TGWC and low SMMI. Low SMMI (Hazard ratio and 95% confidence intervals: 1.45; 1.13- 1.87) and high-TGWC (1.61; 1.13-2.29) were independently associated with total mortality in elderly men, but only low SMMI (1.63; 1.20-2.22) was significant in elderly women. Furthermore, combined low SMMI and high-TGWC had more than 6.8-fold and 3.2-fold risk for cardiovascular mortality, respectively in men and women, compared to the controls (normal SMMI and normal -TGWC). Conclusions: Elderly persons with both abdominal obesity and low skeletal muscle mass were higher mortality risk. Resistance training to maintain skeletal muscle mass may prolong life among the elderly persons.