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Protein Kinase C Alpha Expression in Human Hepatocellular Carcinoma
並列摘要
Protein kinase C (PKC), which contains ten isozymes with distinct enzymological characteristics and intracellular localization, has been believed to be correlated with tumor proliferation, migration and invasion. A recent study found that the PKCα was significantly expressed in the human hepatocellular carcinoma (HCC), and positively correlated with tumor size, tumor stage and mortality rate. It was also found that PKCα played a critical role in cell proliferation, migration and invasion of the poorly differentiated human hepatoma cell lines (HA22T/VGH and SK-Hep-1). In this review, the PKCα signaling in both down-stream and up-stream pathways in HCC cells was discussed.
被引用紀錄
王山富（2008）。腐植酸促進A549肺癌細胞轉移之體外研究〔碩士論文，中山醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0003-2107200811013700
延伸閱讀
- Cheung, K. T. (2007). Expression of integrin-linked kinase in hepatocellular carcinoma [master's thesis, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-1812201200017983
- Tsai, J. H., Tsai, M. T., Su, W. W., Chen, Y. L., Wu, T. T., Hsieh, Y. S., Huang, C. Y., Yeh, K. T., & Liu, J. Y. (2005). Expression of Protein Kinase C Alpha in Biopsies and Surgical Specimens of Human Hepatocellular Carcinoma. The Chinese Journal of Physiology, 48(3), 139-143. https://www.airitilibrary.com/Article/Detail?DocID=03044920-200509-48-3-139-143-a
- 盧秀琴（2010）。Analyzing the Expression of Protein Kinase C Family in Human Hepatocellular Carcinoma〔博士論文，中山醫學大學〕。華藝線上圖書館。https://doi.org/10.6834/CSMU.2010.00018
- Chan, J. (2010). Oncogenic role of integrin-linked kinase in hepatocellular carcinoma [master's thesis, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-1812201200018269
- Cheung, M. T. (2011). Expression of met receptor tyrosine kinase in hepatocellularcarcinoma [master's thesis, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-1812201200019219