This paper describes the work aimed to develop a thermal inkjet (TIJ) printhead with multi-channel driven simultaneously. It proposed a novel data encoding algorithm to control the high voltage multiplexer for multi-channel printhead jets and used bulk micromachining technology (MEMS). The time interleaving scanning sequence is controlled spatially on the jet elements to avoid the strong interference caused by the excitation of the neighbor elements. The simulation and experience result has shown the rid of droplet noise interference. It is reduced nearly half the time compared to the case with traditional scanning sequence. This experiment develops new structure designs of chip for inkjet printheads. A thermal inkjet device is designed, several of the architectures may be adjusted just a few microns to change or optimize the drop generation performance. This energy conversion devices and systems based on integrated driver head with the performance of high-frequency and pico-liter drop inkjet and structures. The TIJ process is akin to an internal combustion engine driven by an explosive phase change rather than an oxidation. In cooking, boiling is experienced as a process with an unpredictable beginning, following the lighting of the cooking flame. The droplet ejection of the multiplexer printhead with 10μm diameter nozzle has been characterized at a frequency over 28kHz, 3pL of ejected droplet volume.