In this article a description of the Orlicz difference sequence space e(subscript M)(Δ(subscript (m)) generated by Orlicz function M and a new generalized difference operator (Δ(subscript (m)) is presented. We investigate some topological structures relevant to this space. It is also shown that under certain condition e(subscript M)(Δ(subscript (m)) is topologically isomorphic to e(subscript ∞). Furthermore we define a subspace h(subscript M)(Δ(subscript (m)) of e(subscript M)(Δ(subscript (m)) and it is shown that under certain condition h(subscript M)(Δ(subscript (m)) is topologically isomorphic to c0.