體脂肪對青年肥胖女性血壓和心臟血流動力學的負面影響

近年來科技的進步，許多不正常的生活模式下累積而成過大的腹部或內臟脂肪組織，形成肥胖人數年輕化日趨增多，當有過大的腰圍或內臟脂肪組織時，肥胖所造成的主動脈狹窄時，左心室血液射出阻力上升，左心室的充氧血無法很順暢的射出，導致左心室舒張期順應性下降，舒張末期壓力升高，此類現象多在過度肥胖出現，但對於年輕肥胖女性，累積過多的脂肪，是否也會在血壓及心臟血液動力學等各項參數有所同樣趨勢，因此本研究目的：1.探討年輕肥胖女性全身體體脂肪%與各項血壓參數的相關；2.探討年輕肥胖女性全身體體脂肪%與各項心臟血液動力學參數的相關。方法：共招募54位年輕女性受試者（年齡：M=21.72±1.78、體重：M=75.81±8.76、體脂肪%：M=39.14±3.93），利用血壓計及血液動力學分析儀，分別針對血壓及心臟血液動力學參數進行檢測。所得基本資料及各項參數，進行描述統計；利用皮爾森績差相關針對體脂肪與各項參數進行相關考驗，利用SPSS24.0統計軟體進行分析，顯著水準為α=.05。結果：1.在『血壓』各參數中，體脂肪與安靜心跳、脈壓明顯呈現正相關聯（p＜.05），分別為r（52）=.324,p=.017及r（52）=.311,p=.022；2.在「血液動力學」各參數：FAT%與SVI：r（52）=-.333,p=.014，呈現明顯負相關；而體脂肪與EDFR%：r（52）=.292,p=.032，呈現正相關（p＜.05）。結論：1.年輕肥胖女性的體脂肪%對於血壓參數是有影響的；2.年輕肥胖女性的體脂肪%對於血液動力學參數是有影響的。

關鍵字

肥胖；脂肪；心臟血液動力學；血壓

並列摘要

INTRODUCTION: Modern technology brings convenience to our life, but greatly reduces opportunities for physical activities, which is a main cause of excessive accumulation of fat in of the body, leading to obesity. Cardiopulmonary endurance in obese individuals is much lower than that of non-obese counterparts, and obese people are prone to cardiac aortic stenosis affecting cardiac hemodynamic and blood pressure, reducing physical fitness further and threatening the health. It should be noted that the age that obesity is developed has become younger and younger. This study investigated the relationships between the body fat percentage (%BF), blood pressure and cardiovascular hemodynamic parameters in young obese women. METHODS: Fifty-four young (20-24 y) obese (≥28%BF) women were recruited for this study. Resting heart rate (HR), systolic (SBP) and diastolic blood pressure (DBP), pulse pressure, SVI, cardiac output: CO, cardiac index: CI, ventricular ejection time: VET, early diastolic filling rate: EDFR%, end diastolic volume: EDV, end systolic volume: ESV, ejection fraction: EF%) were assessed. These variables were analysed by Pearson product-moment correlation coefficient for the relationships with %BF. RESULTS: The %BF ranged between 31.0% and 47.1% among the participants. The %BF had a positive correlation (p＜0.05) with resting HR (r=0.333), pulse pressure (r=0.288) and EDFR% (r=0.275), and a negative correlation (p＜0.05) with SVI (r=-0.384). However, no significant (p＞0.05) correlations between %BF and SBP (r=0.266), DBP (r=-0.041), MAP (r=0.085), SV (r=0.003), CO (r=0.240), CI (r=-0.038), VET (r=-0.040), EDV (r=0.094), ESV (r=0.141), and EF% (r=-0.129) were observed. CONCLUSION: These results showed that obesity increased negative effects on some of the blood pressure and cardiac hemodynamics parameters. Physical activities have to be increased, but endurance exercises do not appear to be suitable, thus eccentric resistance exercise training including eccentric cycling might be a good start.

並列關鍵字

Obese ； Fat ； Cardiac Hemodynamics ； Blood Pressure

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體脂肪對青年肥胖女性血壓和心臟血流動力學的負面影響

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