In the setting of cardiac arrest, ventricular fibrillation and pulseless ventricular tachycardia and considered, shock-treatable rhythms. They have a higher resuscitation rate than either asystole or pulseless electrical activity. However, there are occasions when ventricular fibrillation does not respond to standard defibrillator shocks. Herein, we present a case of successful termination of refractory ventricular fibrillation by double sequence defibrillation. The case later received percutaneous coronary intervention. He was discharged with neurological performance intact.