This work was targeted to enhance the activity of the silver catalyst for low temperature oxidation of VOCs. The methodology used to meet the goal was the optimization of the loading of the Silver-manganese-cerium catalyst. The activity of Ag-Mn-Ce, 20-40-40 mole ratio, is higher than the other catalysts for IPA and Acetone oxidation. The results show the of T98 of IPA and Acetone were 190℃ and 200℃, respectively. The complete oxidation was obtained in the case of IPA by silver catalysts.