The purpose of this article was to stress the importance of exercise prescription for individuals with intellectual disabilities (ID). Individuals with ID are not able to acquire the exercise benefits due to their physical inactivity and low cognitive development. Although special education teachers in Taiwan have limited training on basic sports medicine, exercise prescription can be used to evaluate the individual's body condition from scientific perspectives, and further to design an individualized exercise plan according to the student's personal needs. It is expected that exercise prescription will avoid the unnecessary injury, and improve the quality of life for individuals with ID.