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以似狼瘡性肺炎來表現的肺腺癌

Lung Adenocarcinoma Presenting as Lupus-like Pneumonitis

摘要


我們報告一位34歲年輕女性在就醫前已有乾咳症狀二個月。胸部X光片顯示雙側間質性肺炎,抽血發現高效價抗核抗體,給予抗生素及類固醇治療失敗後,肺部切片結果證實為肺腺癌。對一個血液具高效價抗核抗體陽性且不具其它特異性抗原的年輕病人,除了要考慮自體免疫或結締組織疾病外,尚要考慮腫瘤的可能性。

並列摘要


A 34-year-old female presented with dry cough for 2 months. Chest X-ray showed bilateral interstitial pneumonitis. Her blood anti-nuclear antibody (ANA) titer was 1: 1280. The lung lesions did not respond to ceftazidime or steroids. A subsequent lung biopsy revealed lung adenocarcionoma. In patients with high ANA titer but without specific antibodies to DNA or extractable nuclear antigens, the possibility of underlying neoplastic diseases has to be considered.

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