Dual-time Point FDG PET-CT Imaging of Pulmonary Sclerosing Hemangioma Presenting as Solitary Pulmonary Nodule

肺硬化性血管瘤在雙相正子電腦斷層掃描之表現

李佩瑛(Pei-Ing Lee) ； 游冬齡(Dong-Ling You) ； 劉家全(Chia-Chuan Liu) ； 施志勳(Chih-Hsun Shih) ； 李明媛(Ming-Yuan Lee) ； 黃玉儀(Yu-Yi Huang)

《台灣癌症醫學雜誌》 28卷3期 (2012/09) Pp. 107-112

https://doi.org/10.6323/JoCRP.2012.28.3.1

摘要

目的：硬化性血管瘤是少見的肺部腫瘤，其原發於肺實質內的肺泡型II細胞。本研究目的為探討硬化性血管瘤在雙相正子電腦斷層掃描的表現。材料和方法：本研究總共收集四位接受雙相正子電腦斷層掃描後證實患有肺硬化性血管瘤之病人。早期正子造影及延遲正子造影分別於注射氟-18-去氧葡萄糖（FDG）後60分鐘及180分鐘進行。我們進一步計算腫瘤之早期FDG最大攝取值（SUVmax），延遲FDG最大攝取值（SUVmax），兩次造影之SUV變化率（ΔSUVmax）。結果：肺硬化性血管瘤之早期SUVmax範圍從1.0至5.1，延遲SUVmax範圍從1.0至4.8。一個血管瘤於延遲造影時呈現SUVmax升高，兩個血管瘤於延遲造影時呈現SUVmax降低，其餘一個無明顯之SUVmax變化。結論：本研究發現肺硬化性血管瘤於早期造影呈現低至中度FDG攝取增加情形。肺硬化性血管瘤於延遲造影呈現SUVmax降低或無明顯變化之情況。雙相正子電腦斷層掃描可能有效鑑別此血管瘤之良性特質。

關鍵字

雙相、正子電腦斷層掃描 ； 肺硬化性血管瘤

並列摘要

Background: Sclerosing hemangioma of the lung is a rare neoplasm deriving from pneumocyte type II cells. The objective of this study is to describe the characteristics of pulmonary sclerosing hemangioma on dual-time point FDG PET-CT scan. Methods: We reviewed dual-time point FDG PET-CT scans of 4 patients with proven pulmonary sclerosing hemangioma. Early and delayed FDG PET-CT scans were performed at one and three hours after intravenous injection of FDG. The SUVmax of early and delayed scans and the percent change in SUVmax between the two time points were measured. Results: Early SUVmax of these tumors ranged from 1.0 to 5.1, and delayed SUVmax ranged from 1.0 to 4.8. One tumor showed increased SUVmax on delayed study, 2 tumors showed decreased SUVmax while the remaining tumor showed no change in SUVmax. Conclusions: Pulmonary sclerosing hemangioma shows low to moderate FDG uptake on early PET-CT scan, and minimal change to even lower SUVmax on delayed study. Dual-time point FDG PET-CT may be useful in characterizing the benign nature of these lesions.

並列關鍵字

dual-time point ； FDG PET-CT ； pulmonary sclerosing hemangioma