注射副甲狀腺素對停經後婦女骨質疏鬆症的影響

Effects of Injection of Parathyroid Hormone（PTH）to the Osteoporosis of the Women with Post-Menopause

李侑軒(You-Shiuan Lee)

《2008年台灣銀髮族休閒運動與健康產業發展學術研討會論文集》 2008年 (2008/12) Pp. 173-178

https://doi.org/10.29435/2008YINFA.200812.0173

摘要

骨質疏鬆症的發生最主要是骨質新生速度低於骨質再吸收的速度。理想的防患或治療方法是讓骨質新生的速度與再吸收的速度維持平衡。過去治療骨質疏鬆症的藥物，均為減少破骨作用（bone resorption）進而減緩骨質流失。2002年12月，美國食品藥物管理局（FDA）核准副甲狀腺素（parathyroid hormone, PTH）用於治療停經後有高危險性骨折之骨質疏鬆症婦女，其獨特的作用機轉能刺激造骨細胞，促使新的骨骼生成並增加骨質密度與強度，這無非是提供了停經後的婦女對抗骨質疏鬆症的另一項新選擇。

關鍵字

副甲狀腺素 ； 骨質疏鬆症 ； 骨質密度

並列摘要

Osteoporosis occurs mainly that the speed of newborn of bone mineral slower than that of resorbence of it. The best of prevention or treatment is to keep the balance of the speed of newborn and resorbence of bone mineral. The medicine of treatment of Osteoporosis in past time was to reduce the bone resorption and then decrease the loss of bone mineral. The FDA in December of 2002 approves parathyroid hormone (PTH) to treat the Osteoporosis women with post-menopause who have the high risky bone fracture. The unique function to stimulate the osteoblast both advance the growth of new bone and increase the density and strength of bone mineral provides the other new choice which the women with post-menopause resist Osteoporosis.

並列關鍵字

parathyroid hormone ； Osteoporosis ； bone mineral density