硫辛酸與肌酸增補介入游泳訓練對血漿生化指標的影響

The Effects of Alpha-Lipoic Acid and Creatine Supplementation on Biochemical Parameters in Swimming Training

姚承義(Chen-Yu Yau) ； 梁衍明(Yen-Ming Lian) ； 馮柏菁(Po-Ching Feng) ； 沈淑貞(Shu-Chen Shen)

《大專體育學術專刊》 93年度 (2004/05) Pp. 352-359

https://doi.org/10.6695/AUES.200405_93.0038

摘要

游泳選手在極端環境從事艱苦的訓練，生理承受的衝激頗大。肌酸增補在運動競技上使用頻繁，目前已知其生理效應專注於速度、肌力與爆發力等之能量系統，惟研究結果有效或無益各半；至於副作用或對健康的影響，並沒有特別受到重視。硫辛酸是極強的抗氧化劑，除協助產生能量外，對維生素E、C和麩胱胺酸亦有促進再生循環功能，素有”universal antioxidant”之稱。本研究利用賽前集訓期，目的在探討四週硫辛酸與肌酸介入激烈游泳訓練對血漿生化指標的影響。5位受過良好游泳訓練的大學健康男性運動員為受試者，平均年齡21.00±0.71歲；體重73.20±8.46公斤；BMI 24.26±2.30，彼等接受每週5天的訓練，單次訓練質量為以平均85-90%最大保留心跳率，分段完成3000-3500m距離。第一週每日給予純化肌酸20g，後三週則日給5g，每日訓練前囑服用綻劑硫辛酸100mg。運動評估棒、以85-90%之運動強度，完成20越50公尺捷泳衝刺；評估前後均採肘前肱靜脈血，分析AST、ALT、LDH、CK、肌酸酐及乳酸等生化指標；再以t-test檢定所得資料。結果顯示AST、ALT、LDH三者變化量在3.75%-23.08%，三者所有值均落在正常範圍；硫辛酸增補後CK之後測值顯著減少65%，肌酸酐增加約6%，惟數值均屬異常。故本研究認為四週硫辛酸與肌酸增補介入游泳訓練，對訓練造成肝臟功能負擔及肌肉的損傷有舒緩衝的效果，此應是硫辛酸的作用，對腎臟則否；整體而言，50公尺捷泳運動表現因此提升。

關鍵字

游泳訓練 ； 生化指標 ； 硫辛酸 ； 肌酸

並列摘要

Oral supplementation creatine (Cr) has been used as a strategy for performance enhancement, especially for repeated sprints, maximal power, and speed. High-intensity exercise. Beside, there has unknown that combine Cr and ALA (Alpha-lipoic acid) supplementation on biochemical parameters in swimmers. Five active and well-trained, male swimmers (21.00±0.71 yr.; 73.20±8 .4 6 kg; BMI: 24.26±2.30) were given dietary both creatine (20g/d in 1st wk. then 5g/d in last three wk.) and ALA (100 mg/d); training schedule (3000-3500m/d, 5d/wk, 85-90 % HRR reserve). The experiment lasted 4 weeks in total. Test protocol was set 20 x 50m at 85-90 % HRR. Blood samples were obtained to assess AST, ALT, LDH, CK and creatinine from pre- and post test. Student t-test was used for data analysis. Result show AST, ALT, LDH change rate from 3.75%-23.08%, CK decreased 65% obviously, creatinine increased 6% after ALA supplementation in training. Our study conclude that ALA and Cr supplementation reduced CK concentration and hepatic stress but kidney, meanwhile improve 50m sprint performance in four weeks swimming training.

並列關鍵字

swimming ； biochemical parameter ； alpha-Iipoic acid ； creatine