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Prenatal MR Imaging of Hemimegalencephaly in the Second Trimester
摘要
Hemimegalencephaly (HME), which is defined as an overgrowth of all or part of one cerebral hemisphere, is a rare congenital malformation involving defects in neuronal proliferation, migration, and organization. Prenatal diagnosis can be difficult, unless confirmed through magnetic resonance imaging (MRI). We report the MRI findings of a 22-week-old fetus with HME. The MRI study showed extensive overgrowth of the entire left cerebral hemisphere, with an indistinct corticomedullary junction. Diffusion imaging showed restricted diffusion in the ipsilateral central subependymal region. We proposed that the increased cellularity of dysplastic stem cells may account for the restricted diffusion in the subependymal region. This type of location of the restricted diffusion may be associated with the extensive malformation of the cerebral mantle.
延伸閱讀
- Huang, L. C., Hung, Y. C., Chen, L. M., Chiu, T. H., & Ho, M. (2007). Magnetic Resonance Imaging for Prenatal Diagnosis: An Adjunct Diagnostic Tool. Mid-Taiwan Journal of Medicine, 12(4), 198-202. https://doi.org/10.6558/MTJM.2007.12(4).4
- Shen, C. C., Lui, C. C., Hsu, T. Y., & Chang, S. Y. (2003). Prenatal Diagnosis of Alobar Holoprosencephaly Facilitated by the Combined Use of Ultrasound and Magnetic Resonance Imaging. Taiwanese Journal of Obstetrics & Gynecology, 42(3), 187-192. https://doi.org/10.29787/TJOG.200309.0006
- Murata, S., Nakata, M., Sumie, M., Mastsuabra, M., & Sugino, N. (2009). Prenatal Diagnosis of Pentalogy of Cantrell with Craniorachischisis by Three-Dimensional Ultrasonography in the First Trimester. Taiwanese Journal of Obstetrics & Gynecology, 48(3), 317-318. https://doi.org/10.29787/TJOG.200909.0025
- Ho, M., Lee, C. C., Chang, Y. Y., Tai, C. T., Chen, T. C., Yeh, L. S., & Tsai, H. D. (2003). Diagnosis of an Angular Pregnancy in the First Trimester Using Three-dimensional Ultrasound. Taiwanese Journal of Obstetrics & Gynecology, 42(2), 141-145. https://doi.org/10.29787/TJOG.200306.0010
- Ke, C. S., Chu, T. W., Yu, M. H., Yin, C. S., Chu, C. C., & Diau, G. Y. (1997). Prenatal Diagnosis of Fetal Congenital Hiatal Hernia. Journal of Medical Sciences, 17(4), 239-242. https://www.airitilibrary.com/Article/Detail?DocID=10114564-199702-201306140012-201306140012-239-242