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Should We Rely on Milder or Severer Degree of Coronary Artery Stenosis in Different Cardiac Phases of Coronary Computed Tomography Angiography?

摘要


PURPOSE. To compare the reliability of two different cardiac phases in coronary computed tomography angiography (CTA) in predicting further clinical decision. MATERIALS AND METHODS. A total of 19 patients without or with stable chest pain undergoing coronary CTA with two different cardiac phases were included in this retrospective study. The two different cardiac phases were categorized as the milder phase and the severer phase. Forty-seven segments of coronary arteries were analyzed. Both segment-based and patient-based analyses were performed. Whether or not subsequent examinations was arranged was used as gold standard. RESULTS. Under segment-based analysis, there was no significant difference in sensitivity (73.3 vs. 80%, p = 1.000) and specificity (84.4 vs. 71.9%, p = 0.125) with respect to the phases of milder and severer stenosis. Five segments showed discordant results in different cardiac phases and only one of them underwent further invasive coronary angiography, with non-significant stenosis. Under patient-based analysis, similarly, there was no significant difference between the diagnostic performance of the two phases (sensitivity = 100.0 vs. 100.0%; specificity = 64.3 vs. 57.1%, p = 1.000). Only one patient had discordant results in two phases, without further cardiac investigation. CONCLUSION. Despite a lack of significant difference in the ability to predict further clinical decision between milder and severer cardiac phases on coronary CTA, the milder degree of stenosis seems to be more reliable when the results are discordant in different cardiac phases.

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