Top-Grafted pear is a unique sand pear production method of Taiwan, which top-grafted high chilling requirement temperate-zone sand pear on local sand pear to produce high quality pear. The factors affected top-grafted pear production were the flower bud condition of scion, healing of graft unit, pollen source and pollinators, nutrient competition during ovule development, environment condition, and the physiological and nutritional condition of the root-stock. Orchard management during scion flower bud formation, plentiful nutrients accumulation, regulations of dormancy and nutrient supply of the root-stock during grafting, timing of grafting, pollinizer and hand pollination, and optimum pollinators and flowering condition could promoted fruit set of the pear. Moreover, the timing of grafting according to the weather data and by the irrigation water warming for fruit set improvement is discussed in this article.