According to Ministry of the Interior, population of elders reached 2.7 million (11.53% of national population) in 2013. To allow elders to age in place and consequently relieve the burden on their families, elderly day care centers serve elders with disabilities and dementia by providing assistance in daily activities. The environment of day care centers plays a crucial role in space use and quality of care. This paper discussed the development of elderly day care centers in developed countries and Taiwan, and related issues, in order to establish the guidelines of selecting location and building type and planning and designs for architects and interior designers. Quality of space use and care services may be enhanced through effective space and indoor planning and designs.