Aconite roots has strong spicy and hot flavor. It is a commonly prescribed Chinese medicine for recuperating depleted yang and expelling cold and pain in patient. In this article, we discussed the preparation methods, influence of decocting on the efficacy therapeutically, toxicity and reverse reaction of aconite roots. Besides, we conclude our experience from the viewpoints of clinical practice to elucidate the pharmacological effects, indications of prescription, pharmaceutic incompatibility of aconite roots for clinicians' references.