Data transformation is an important statistical analysis tool. Box-Cox transformation is one of important data transformations. This paper derives estimators of normal distribution parameters with Box-Cox transformation by using of maximum likelihood method and then discussed their unbiased estimator and consistency estimator, obtains the distributions of the sample mean and variance of Box-Cox transformation which is valuable to interval estimation and test of normal distribution parameters with Box-Cox transformation. A real example is used to illustrate the proposed methodologies.