Malignant Pleural Mesothelioma with Extensive Skeletal Muscle Metastasis

惡性間皮癌病患併瀰漫性骨骼肌肉內轉移

江佳駿(Chia-Chun Chiang) ； 謝明書(Ming-Shu Hsieh) ； 張端瑩(Dwan-Ying Chang)

《台灣癌症醫學雜誌》 1卷2期 (2014/09) Pp. 134-139

https://doi.org/10.6323/JCRP.2014.1.2.06

摘要

我們報告一位61歲之惡性間皮癌病人併發瀰漫性的骨骼肌肉內轉移，病人初始症狀為肌肉僵硬及無力。磁振造影及電腦斷層顯示為數眾多大小不一腫瘤分布於全身的骨骼肌肉內，病理切片輔助螢光免疫染色法證實為轉移性惡性間皮癌。病人病況迅速惡化，很快就變得不能移動而臥床，失去自我照顧能力且併發肺炎，最後死於呼吸衰竭。儘管接受了化學治療，距離症狀開始，病人仍只存活了三個月。我們探討此案例骨骼肌肉內轉移的臨床表現及意義，並回顧了過往間皮癌病人骨骼肌肉內轉移的病例報告。

關鍵字

惡性間質瘤 ； 骨骼肌轉移 ； 正子攝影

並列摘要

We treated a 61-year-old man with malignant pleural mesothelioma complicated by extensive skeletal muscle metastases. The initial presentation included rapidly progressive weakness and stiffness in four extremities. The magnetic resonance image (MRI) and the computed tomography (CT) scan revealed disseminated symmetrical intramuscular nodular lesions. Excisional biopsy was taken and pathology confirmed the presence of a biphasic metastatic mesothelioma by immunohistochemical (IHC) staining. The patient survived for only 3 months from the onset of the symptoms despite of the administration of emergency chemotherapy and optimal supportive care.

並列關鍵字

malignant pleural mesothelioma ； skeletal muscle metastases ； positron emission tomography