Castleman's Disease Incidentally Detected by F-18 FDG PET/CT: A Case Report and Literature Review

正子造影意外發現之淋巴結增生性疾病

陳柏因(Po-Yin Chen) ； 胡瑨(Gin Hu) ； 彭南靖(Nan-Jing Peng)

《核子醫學暨分子影像雜誌》 29卷3期 (2016/09) Pp. 143-147

https://doi.org/10.6332/ANMMI.2903.005

摘要

Castleman's disease是少見的良性淋巴增生性疾病，又稱為巨大淋巴結增生(giant lymph nodc hyperplasia)或血液濾泡淋巴結增生(angiofollicular lymph node hyperplasia)。胸腔位好發位置，較少發生在胸腹部和頸部。可能無症狀或是表現淋巴腫大合併系統性症狀(發燒、體重減輕、貧血等)。可分玻璃樣血管型和漿細胞兩種組織學表現，以玻璃樣血管型為大宗，預後較好。漿細胞常合併多發性表現和全身性症狀，可能與HIV和HHV-8感染相關。在氟-18去氧葡萄糖正子電腦斷層攝影中多是中等程度程度葡萄糖吸收，若代謝性很強常在多發性的案例中發現，一般預後也較差。我們報告一個因皮膚症狀懷疑潛在腫瘤，後來經氟-18去氧葡萄糖正子電腦斷層攝影在後腹腔發現一個低度至中等攝取程度的單一腫瘤，經手術移除後病理報告確診為Castleman's disease。

關鍵字

血液濾泡淋巴結增生 ； 巨大淋巴結增生 ； 氟-18去氧葡萄糖 ； 正子斷層造影 ； 淋巴癌

並列摘要

Castleman's disease is a rare lymphoproliferative disorder, alternatively referred to as giant lymph node hyperplasia or angiofollicular lymph node hyperplasia. It's histopathologically classified into 2 types: Hyaline- Vascular type and Plasma cell type. The hyaline-vascular cases usually are asymptomatic and unicentric, whereas the less common plasma cell type may present with multicentric and systemic symptoms, sometimes related to HIV or HHV-8 infection. We report a 40-year-old man who has unicentric plasma cell type Castleman's disease incidentally found by F-18 FDG PET/CT with mild-tomoderate metabolism.

並列關鍵字

angiofollicular lymph node hyperplasia ； Castleman’s disease ； F-18 FDG PET/CT ； giant lymph node hyperplasia ； lymphoma