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A Rare Case of Concordant NP-59 Scintigraphy Adrenal Carcinoma with Synchronous Castleman's Disease

病例報告:腎上腺皮質掃描顯影之腎上腺皮質癌併Castleman氏病

摘要


Concordant norcholesterol radiotracer uptake adrenocortical carcinoma is rare and thought to be related with functioning status and cellular differentiation. We report a 56-year-old female who received NP-59 scan under the surveillance of suspicious Cushing’s syndrome. A left adrenal tumor was found on computed tomography, which at the same time revealed a left lower abdominal mesenteric mass. NP-59 scan showed concordant radiotracer accumulation in left adrenal tumor and no radiotracer accumulation in the mesenteric mass. Pathological examination confirmed left adrenal cortical carcinoma, while the mesenteric mass was favored to be Castleman's disease. To our knowledge, this is also the first case of co-occurrence of adrenocortical carcinoma with Castleman's disease.

並列摘要


在NP-59腎上腺皮質掃描表現為吸收增加的腎上腺癌相對稀少,一般認為與腫瘤之功能性以及細胞分化相關。一位56歲女性因為高血壓,低血鉀合併庫欣氏症表徵,懷疑有腎上腺皮質瘤而接受腹部電腦斷層以及NP-59腎上腺皮質掃描。電腦斷層顯示一顆左腎上腺結節,另有偶然發現的腸系膜腫瘤。腎上腺皮質掃描顯示左腎上腺腫瘤相對應同位素吸收增高,懷疑功能性腎上腺皮質瘤。手術後病理結果為腎上腺皮質癌與Castleman氏病。此案例亦為所知的第一例併存的腎上腺皮質癌與Castleman氏病。

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