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Short-term and long-term outlook after eventually successful albeit transiently complicated percutaneous coronary intervention for chronic total occlusion: The Rivoli chronic total occlusion registry

摘要


Aims: We aimed to appraise the outlook of successful albeit transiently complicated percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). Percutaneous coronary intervention of CTO may improve symptoms, systolic function and prognosis, but may be associated with short-term complications. Methods: Baseline, procedural and outcome details on patients in whom CTO PCI was attempted between 2003 and 2012 at our institution were retrieved. We compared those with failed PCI (F group) to those with successful and uncomplicated PCI (SU group) and those with eventually successful albeit transiently complicated PCI (SC group). Results: A total of 435 patients were included, with 25.7% failures and 74.3% successes, including 67.8% in the SU group and 6.4% in the SC group. One-month major adverse cardiac events (MACE) occurred in 0.4% patients in the SU group, 7.1% in the SC group, and 2.7% in the F group (p=0.005). Risk of major adverse cardiac events (MACE) after one month was similar in patients in the SU and SC groups, with both groups faring better than those in the F group (respectively 23.7%, 17.9%, and 18.8%, p = 0.477). Similar trends for >1-month events were found for death and myocardial infarction (both p > 0.05), whereas repeat revascularization was more common after SU group (19.3% versus 14.3% and 6.3%, p = 0.005). Stent thrombosis was more common in SC group (0 versus 7.1% and 1.8%, p < 0.001). Conclusion: Patients with uncomplicated CTO recanalization are at higher risk of restenosis and revascularization, whereas those with final success despite complications are at higher risk of stent thrombosis.

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