There are a rather large number of studies on theoretical investigation of behavior of buildings with tuned mass dampers under various impacts. However, the experimental studies in this area are quite limited. This work to a certain extent fills the gap in experimental studies aimed at investigation of behavior of buildings with tuned single and double mass dampers. Based on these investigations different types of dampers were designed and implemented for seismic protection of existing buildings. Linear and nonlinear analyses and dynamic tests of these buildings were carried out confirming the efficiency of tuned mass dampers.