- 期刊
卵巢混合性生殖細胞腫瘤之復發及惡性轉形：病例報告與文獻回顧
Recurrent ovarian mixed germ cell tumor with unusual malignant transformation: a case report
摘要
卵巢混合性生殖細胞腫瘤（ovarian mixed germ cell tumor）存活率通常良好，然若在重複減積手術及化療後仍復發，預後相對不佳，臨床醫師應審慎評估病人之危險因子，確立個別化的治療方針及追蹤策略；本文報告一卵巢混合性生殖細胞腫瘤病例合併罕見之惡性轉化（malignant transformation）組成，且存有畸胎瘤不成熟成分化學治療反轉化的現象（chemotherapeutic retroconversion），並回顧現有相關文獻。
並列摘要
The value of this report is the identification of late recurrence with an extremely unusual combination of malignant transformation. In particular, the retrocon-version of immature to mature teratoma as well as a somatic-type malignant transformation were both observed postchemotherapeutically in our case. Recurrent disease after repeated cytoreduction and chemotherapy hints a poor outcome despite a generally excellent long-term survival rate among ovarian germ cell malignancies. It is important for clinicians to distinguish those at risk of poorer outcomes and establish individualized postoperative surveillance. Fertility-compromising surgery may be considered in selected patients.
延伸閱讀
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