Ionic Liquid-Modified Silica as Solid Phase Extraction Material Coupled with Spectrofluorimetry for the Analysis of Honokiol and Magnolol in Traditional Chinese Medicine

Ai-Qin Gong ； Ting-Ting Hou ； Xia-Shi Zhu

《Advances in Chemical Science》 2卷3期 (2013/09) Pp. 68-77

並列摘要

Novel ionic liquid-modified silica particles (IL-SiO_2) were prepared by the surface chemical modification of the commercial silica. The obtained ionic liquid-modified particles were successfully used as solid-phase extraction (SPE) material coupled to fluorescence spectroscopy for the determination of honokiol and magnolol which are active constituents of traditional Chinese Medicine. Several factors influencing the pre-concentration/separation of honokiol and magnolol were discussed in details. Under the optimal conditions, the adsorption efficiencies of honokiol and magnolol with IL-SiO_2 as sorbents were much higher than those with bare silica (IL-SiO_2: 97.2%, 96.6%; SiO_2: 17.6%, 2.5%). The adsorption capacities of IL-SiO_2 for honokiol and magnolol were 6.9 mg•g^(-1) and 6.0 mg•g^(-1). The linear range of calibration curve for the determination of honokiol and magnolol was 0.015-7.60, 0.008-5.00 μg•mL^(-1), and the limit of detection (LOD) was 2.6, 1.3 ng•mL^(-1), respectively, with enrichment factor of 6. The developed method was successfully applied to the determination of honokiol and magnolol in Huoxiang Zhengqi Shui.

並列關鍵字

Ionic Liquid-Modified Silica ； Honokiol and Magnolol ； Solid-Phase Extraction ； Spectrofluorimetry