The paper presents a unified novel approach to structural synthesis, analysis and parameters identification of all the acceptable multiloop mechanical systems on base use a new topological properties of closed kinematic chains. Shown many examples of the direct number structural synthesis, structure analysis and fastest isomorphic identified of simple and multiple joint chains, executed on base a new topological mobility equations and by an original "rank link matrix". The examples to studies various planar and spatial mechanical systems also shown, that obtained design methodology can be successfully used to perform other specified tasks at conceptual stage of design statically determinate mechanisms, clamping devices and truss.