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- OpenAccess
Correlation of symptoms of infertile patients with endometriosis with the classification of the American Society for Reproductive Medicine
並列摘要
Background: Endometriosis is a common gynecological disease associated with pelvic pain and infertility. There are discrepancies between the clinical presentation and the degree of the disease, suggesting the necessity of a better understanding of the pathophysiological mechanisms of endometriosis, besides highlighting the lack of a classification that considers the clinical picture of this disease. So, profiling the infertile patients with endometriosis in relation to their symptomatology becomes fundamental in the advancement of knowledge. Methodology: Retrospective cross-sectional study of 450 medical records of infertile women with endometriosis. Symptoms were correlated with the degree of endometriosis and it with personal and obstetric history. Results: The prevalence of dysmenorrhea was higher in more severe forms of the disease. Being in grades Ⅰ, Ⅱ, Ⅲ and Ⅳ, respectively, 101 (74.3%), 56 (81.2%), 82 (87%) and 140 (92.7%), with P = 0.001. The intestinal disorders were more common with increasing grades of the disease: the grades Ⅰ, Ⅱ, Ⅲ and Ⅳ, respectively, 60 (44.1%), 32 (46.4%), 56 (59.6%) and 97 (64.2%) P = 0.002. Family history of endometriosis was associated with grade Ⅲ (P = 0.017), while depression, with grade I (P = 0.032). Conclusion: Dysmenorrhea, intestinal disorders and the presence of a family history of endometriosis were associated with higher degrees of endometriosis. In contrast, depression interestingly presented significant correlation with the grade Ⅰ. Understanding the correlation of infertility with endometriosis and the impact on the symptoms of these patients could help in designing a new and more comprehensive classification for endometriosis.
延伸閱讀
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