血管緊縮素II是一個造成高血壓的內生性荷爾蒙。最近臨床試驗結果顯示血管緊縮素II受體拮抗劑能有效地治療高血壓疾病,本文將介紹血管緊縮素II受體拮抗劑的起源及其最近進展。
Angiotensin II is an important endogenous hormone in causing hypertension. Recent clinical evaluation of angiotensin II antagonists has shown that blocking of the actions of angiotensin II at receptor level has therapeutical effect. In this article, we report the history of angiotensin II antagonist and its recent advances.