核酸與8-羥基喹啉金屬熒光配合物的作用研究

Studies on the Interactions of Fluorescent M(III)/8-Hydroxyquinoline Complexes with Nucleic Acids

黃承志(Cheng-Zhi Huang) ； 李克安(Ke-An Li) ； 童沈陽(Shen-Yang Tong)

《化學》 55卷1期 (1997/03) Pp. 1-6

https://doi.org/10.6623/chem.1997001

摘要

本文報導了核酸對鋁(III)、鈧(III)、釔(III)、和鑭(III)等三價金屬離子[M(III)]與8-羥基喹啉形成的二元熒光配合物的熒光增強特性及其影響因素，對比了核酸和陰離子表面活性劑十二烷基硫酸鈉(SDS)與上述二元配合物的作用，測定了有關體系的熒光壽命，結果表明，核酸與上述二元配合物的作用在于核酸與二元熒光配位離子形成了多元離子締和物，改變了二元配合物在水溶液中的微環境。

關鍵字

核酸 ； 8-羥基喹啉 ； 熒光

並列摘要

This paper presents the enhancement effects of nucleic acids on the fluorescence output of the binary complex formed by 8-hydroxyquinoline and tripositive metallic ions such as AI(III), Sc(III), Y(III), La(Ill), and discusses the affecting factors on the fluorescence enhancement effects. By comparing the fluorescence enhancement effects of nucleic acids with that of sodium dodecyl sulfate (SDS) on the binary complexes, and measuring the fluorescence life time of each system, we supposed that the interactions of fluorescent M(III)/8-HQL complexes with nucleic acids result in multicomponent ion associates and lead to the variations of the microenvironment of the binary complexes in water medium.

並列關鍵字

Nucleic Acids ； 8-Hydroxyquinoline ； Fluorescence