摘要
固相萃取法係利用可拋棄式固相萃取管柱吸附溶液中待測分析物而通過不純物，吸附後再以少量適當溶劑沖提所吸時之待測物，藉以達到濃縮及純化目的之樣品製備方法，所得溶液再經請當儀器分析。利用固相萃取法萃取，其干擾物較液相－液相萃取法少；可提高分析物濃度及回收率，不似液相－液相萃取法需濃縮萃取液造造成分新物之流失。且液相－液相萃取法帶使用大量有機溶液，易造成環境上的污染，固相萃取法通常僅需要數毫升左右溶劑。固相萃取法由於真有純化、濃縮、操作方便、溶劑使用少、可快遠處理樣品、留收率高、裝備簡單、不需特別的實驗握才能擁有、也不需什麼特殊的說術等價點，自此利用固相萃取法於微量物質之萃取技術相當普遍化。故本文針對固相萃取技術之發展過程，原理及應用做一介紹，以供對微量樣品前處理技術有興蘊者之參考。
並列摘要
Solid phase extraction (SPE) is a method of sample preparation that concentrates and purifies analytes from solution by sorption onto a disposable solid-phase cartridge, followed by elution of the analyte with a solvent appropriate for instrumental analysis. SPE uses small volumes of cornmon solvents, requires very simple specialized laboratory equipment and allows rapid sample throughout SPE techniques will usually provide bettersample cleanup and recoveries than liquid-liquid extraction techniques. The developments, principles, mechanisms and applications of SPE technique will be introduced in this article.