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毛細管電動層析之對掌性靜相的發展與應用

The Evolution and Applications of Chiral Stationary Phases for Capillary Electrochromatography

摘要


對掌性異構物的分離不僅在分析化學方面是十分重要的研究課題,其應用性於其他領域,例如:製藥及醫藥科學...等方面也受到相當程度的重視。目前,兼具毛細管電泳及液相層析二者分離優點的毛細管電動層析是提高分析效率及對掌選擇性的新型態分離方式,而其填充的對掌性靜相大部分沿用自液相層析系統,此篇內容將簡單介紹毛細管電動層析的模式及其主要優點,並探討所使用之對掌性靜相的發展與應用。

並列摘要


Enantiomeric separation is an important subject in analytical chemistry and many other areas, including pharmaceutics, medicinal sciences, etc. A new separation mode which combines the advantages of capillary electrophoresis and liquid chromatography is called capillary electrochromatography (CEC). CEC increases both of the efficiency of separation and the selectivity of enantiomeric separation. Most of the chiral stationary phases for CEC are inherented from chromatography. In this review report, the operations and advantages of capillary electrochromatography are described briefly, then the developments and applications of chiral stationary phases are discussed.

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楊妮欣(2013)。以脂肪酶固定化金屬有機骨架材料進行生物性催化合成華法林抗凝血劑〔碩士論文,中原大學〕。華藝線上圖書館。https://doi.org/10.6840/cycu201301002

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