二氧化鈦/奈米銀不織布製備及抗菌活性研究

Preparation and Antibacterial activity of Non-woven Fabric with Titanium dioxide/Silver

楊福助(Fu-Chu Yang) ； 吳國輝(Kuo-Hui Wu) ； 楊琇雯(Hsiu-Wen Yang) ； 黃仁偉(Jen-Wei Huang) ； 林文博(Wen-Po Lin) ； 洪登南(Deng-Nan Horng) ； 胡明寬(Ming-Kuan Hu)

《化學》 67卷1期 (2009/03) Pp. 93-99

https://doi.org/10.6623/chem.2009008

摘要

銀離子 (Ag^+) 具極佳之抗菌性，經奈米化之銀粒子 (Ag) 易釋放出銀離子而達到優異的抗菌效果，本文以具有催化功能的二氧化鈦 (Titanium dioxide, TiO_2) 為載體，奈米銀為抗菌劑，合成二氧化鈦/奈米銀抗菌複合材料，經連續浸染及烘乾過程將不同比例的二氧化鈦/奈米銀抗菌複合材料塗覆於不織布纖維表面，製成抗菌織布，做為抗菌醫療敷料應用研究。本研究以XRD 和SEM (EDX) 分析抗菌織布結構特性、銀含量及抗菌複合材料在纖維上的分散情形。抑菌度/殺菌度試驗則是以革蘭氏陽性 (Gram-positive)-金黃色葡萄球菌 (S. aureus)、枯草桿菌 (B. subtilis)、抗甲氧苯青黴素金黃色葡萄球菌 (MRSA) 及革蘭氏陽性 (Gram-negative)-綠膿桿菌 (P. aeruginosa)、大腸桿菌 (E. coli)、抗環丙沙星綠膿桿菌 (CRPA)、大腸桿菌勝任細胞 (E. coli JM 109) 為目標菌，透過懸液定量殺滅試驗和抑菌環試驗檢測抗菌織布的殺菌及抑菌能力。

關鍵字

二氧化鈦/奈米銀 ； 抗菌織布 ； 金黃色葡萄球菌

並列摘要

Silver ion have a bactericidal activity and nanometer silver particles exhibits a strong bactericidal activity. The titanium dioxide/Ag composites with adsorption and antibacterial efficacy were synthesized and incorporated in fabric matrix to be an antibacterial fabric. These antibacterial fabrics were sterile and could be useful in wound healing and antibacterial material to prevent or to minimize infection with pathogenic bacteria. The titanium dioxide/Ag and its antibacterial fabric were characterized by silver content, silver particle size, distribution and antibacterial properties with XRD and SEM (EDX). Taking Gram-positive(G+)-Staphylococcus aureus, Bacillus subtilis, MRSA and Gram-negative(G-)-Pseudomonas aeruginosa, Escherichia coli, CRPA, E. coli JM 109 as target bacteria, suspension quantitative bactericidal test and inhibitory test were carried out.

並列關鍵字

Titanium dioxide/Ag ； Antibacterial fabric ； Staphylococcus aureus