並列摘要
Silicon nanowire field-effect transistors (SiNW-FETs) have recently drawn tremendous attention to become a promising biosensor because of their ultrasensitivity, selectivity, and labelfree and real-time detection capabilities. Here, we review a few recent publications of SiNW-FET sensors with an emphasis on their device fabrications and biomedical applications. For practical uses, SiNW-FETs can be delicately designed to be a reusable device via a reversible surface functionalization method. In the fields of biological research, SiNW-FETs have been employed in the detections of proteins, DNA sequences, small molecules, cancer biomarkers, and viruses. Finally, the novel design of a three-dimensional nano-FET probe with kinked SiNWs for recording intracellular signals is highlighted in this article.