目的:探討糖尿病個案基本特性、疾病狀況、憂鬱與生活品質的相關性。方法:採橫斷式研究設計及立意取樣方式,以中部某區域綜合醫院新陳代謝科門診之第二型糖尿病患者為收案對象,共計收取有效樣本238人。同時利用結構式問卷收集資料,包括個案基本特性、疾病狀況、Centerfor Epidemiologic Studies Depression Scale(CES-D)中文版量表、台灣簡明版世界衛生組織生活品質問卷。結果:研究對象的平均糖化血色素值為8.5%,生活品質總量表得分為55.3,其中以環境範疇的得分最高,生理健康範疇的得分最低。教育程度、婚姻、治療方式、合併症數目、糖化血色素與憂鬱情緒分別與生活品質各範疇有相關性,治療方式與憂鬱情緒是整體生活品質的重要預測因子,解釋變異量有19.8%。結論:疾病狀況與糖尿病個案生活品質有顯著相關,且與疾病嚴重度有關,醫護專業團隊應提供更完善的衛生教育及照護,努力避免或延緩糖尿病患者使用胰島素治療。憂鬱是糖尿病個案生活品質最重要的預測因子,建議糖尿病管理應更著重於憂鬱情緒的評估,必要時應透過藥物或認知行為的介入治療,以減輕糖尿病個案在疾病和憂鬱情緒的不適,讓患者在生活品質上獲得最大的改善效益。
Objectives:To investigate the association of demography, disease status, depression and quality of life (QOL) in diabetic patients. Methods:A cross-sectional study design and purposed sampling were used. Total 238 type 2 diabetic subjects enrolled in the study from the outpatient of Endocrinology and Metabolism at a General Hospital in the central area of Taiwan. The structured questionnaire included demographic data, disease status, Center for Epidemiologic Studies Depression Scale (CES-D), WHOQOLBREF Taiwan version. Results:The mean glycosylated hemoglobin (HbA1C) value for all participants was 8.5. The mean score for total QOL was 55.3. According to each subscale, the environment scale had highest score while the physical health scale had the lowest score. Education, marital status, treatment regimen, number of complications, HbA1C, and depression were significant correlation with QOL. Treatment regimen and depression were important predictors of QOL, and explained 19.8%. Conclusions:The results showed that treatment regimen significant influenced QOL and correlation with the severity of disease. The health professionals should provide more comprehensive health care, and effort to avoid or postpone insulin treatment for diabetic patients. Depression was the important predictor of QOL for diabetes. The management of diabetes should focus on depression assessment and intervention therapy by medication or cognitive behavior in necessary, so that it would alleviate of suffering in diabetes and depression and should have major benefits in QOL improvement for diabetic patients.