This article depicted the nursing experience of caring a pre-school child with pneumonia combined lung abscess who received surgical treatment. During nursing care period, the author collected the data by listening, un-structured interview, observation, and so on. Holistic care model was applied to detect the following nursing diagnoses: fever, ineffective airway clearance, hyperthermia, pain, and so on. During the nursing process, the author aimed at developing characteristics of pre-school child to apply Therapeutic play and build up the trustworthy relationship. With the improvement of the patient’s fear, this patient could accept the treatment and nursing. The author also matched up the suitable education guidance and provided the family with proper knowledge to gain abilities of caring this patient. Therefore, the patient could receive the optimal care during hospitalization and then got discharged.