「血液幹細胞移植後生活品質」之概念分析

醫療與科技的進步，有越來越多罹患惡性腫瘤病患接受血液幹細胞移植以期達到治癒的目的，病患在移植前的調理治療往往需接受高劑量化學治療及全身放射線治療以達淨空骨髓之目的，此兩項治療皆會帶來嚴重的副作用並影響病患的生活品質，在進行相關研究之前，應先就『血液幹細胞移植後生活品質』之概念作清楚的分析與定義，從文獻中發現移植後生活品質會隨時間進展而有所不同，約一年之後會漸漸改善生活品質。本文係採用Walker & Avant的概念分析步驟進行「血液幹細胞移植後生活品質」概念分析，期許藉此過程更清楚呈現出「血液幹細胞移植後生活品質」概念，並藉由本文中的案例以協助醫療專業人員將生活品質視為一整體性概念以提供全人照護之目的。

關鍵字

血液幹細胞移植；生活品質；概念分析

並列摘要

High-dose chemotherapy and/or radiotherapy followed by hematopoietic stem cell transplantation (HSCT) is increasingly being used because of its curative potential in a subset of patients, however, with the complexity of the treatment come incremental challenges to quality of life of HSCT patients. Several health related quality of life studies focused on the time after the first year posttransplant. This is when subjects could be expected to be more stable. The purpose of this article is to address concept analyses of quality of life and develop a definition applicable for hematopoietic stem cell transplantation patient. The process for concept analysis developed by Walker & Avant is employed, and it is hoped that this analysis will stimulate thought and further nursing research into what QOL means in the health care context.