- 期刊
Tumour necrosis factor-alpha (TNFα) stimulates the growth of human bone marrow stromal cells
摘要
This study reports that TNF-α is a potent mitogen for human bone marrow sternal cells in vitro (assessed by [^3H]-thymidine incorporation into DNA and cell counts). In contrast, cytokines such as IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-6, LIF, SCF, M-CSF, G-CSF and GM-CSF had no effect. The effect of TNF-α on the growth of human bone marrow stromal cells could be of importance during inflammatory processes which take place in the marrow, for example marrow fibrosis.
延伸閱讀
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